Nature Communications (Nov 2017)
Rods progressively escape saturation to drive visual responses in daylight conditions
- Alexandra Tikidji-Hamburyan,
- Katja Reinhard,
- Riccardo Storchi,
- Johannes Dietter,
- Hartwig Seitter,
- Katherine E. Davis,
- Saad Idrees,
- Marion Mutter,
- Lauren Walmsley,
- Robert A. Bedford,
- Marius Ueffing,
- Petri Ala-Laurila,
- Timothy M. Brown,
- Robert J. Lucas,
- Thomas A. Münch
Affiliations
- Alexandra Tikidji-Hamburyan
- Retinal Circuits and Optogenetics, Centre for Integrative Neuroscience and Bernstein Center for Computational Neuroscience, University of Tübingen
- Katja Reinhard
- Retinal Circuits and Optogenetics, Centre for Integrative Neuroscience and Bernstein Center for Computational Neuroscience, University of Tübingen
- Riccardo Storchi
- Faculty of Biology Medicine and Health, University of Manchester
- Johannes Dietter
- Institute for Ophthalmic Research, Department of Ophthalmology, University of Tübingen
- Hartwig Seitter
- Retinal Circuits and Optogenetics, Centre for Integrative Neuroscience and Bernstein Center for Computational Neuroscience, University of Tübingen
- Katherine E. Davis
- Faculty of Biology Medicine and Health, University of Manchester
- Saad Idrees
- Retinal Circuits and Optogenetics, Centre for Integrative Neuroscience and Bernstein Center for Computational Neuroscience, University of Tübingen
- Marion Mutter
- Retinal Circuits and Optogenetics, Centre for Integrative Neuroscience and Bernstein Center for Computational Neuroscience, University of Tübingen
- Lauren Walmsley
- Faculty of Biology Medicine and Health, University of Manchester
- Robert A. Bedford
- Faculty of Biology Medicine and Health, University of Manchester
- Marius Ueffing
- Institute for Ophthalmic Research, Department of Ophthalmology, University of Tübingen
- Petri Ala-Laurila
- Department of Biosciences, University of Helsinki
- Timothy M. Brown
- Faculty of Biology Medicine and Health, University of Manchester
- Robert J. Lucas
- Faculty of Biology Medicine and Health, University of Manchester
- Thomas A. Münch
- Retinal Circuits and Optogenetics, Centre for Integrative Neuroscience and Bernstein Center for Computational Neuroscience, University of Tübingen
- DOI
- https://doi.org/10.1038/s41467-017-01816-6
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 17
Abstract
Rod photoreceptors are thought to be saturated under bright light. Here, the authors describe the physiological parameters that mediate response saturation of rod photoreceptors in mouse retina, and show that rods can drive visual responses in photopic conditions.
