Patient Preference and Adherence (Jul 2021)
Effect of Evidence-Based Pharmacy Care on Satisfaction and Cognition in Patients with Non-Valvular Atrial Fibrillation Taking Rivaroxaban
Abstract
Jie Sun,1,2 Guo-Mei Chen,1,2 Ji Huang1,2 1Department of Pharmacy, The First People’s Hospital of Taicang, Taicang, People’s Republic of China; 2The Affiliated Taicang Hospital of Suzhou University, Taicang, People’s Republic of ChinaCorrespondence: Guo-Mei ChenThe First People’s Hospital of Taicang, The Affiliated Taicang Hospital of Suzhou University, No. 58 Changsheng Road, Taicang, 215400, People’s Republic of ChinaTel/Fax +86-512-53101356Email [email protected]: We aimed to determine the effects of using evidence-based pharmacy care on satisfaction and cognition among patients with non-valvular atrial fibrillation (NVAF) and taking rivaroxaban.Patients and Methods: Between July 2018 and June 2019, 200 consecutive hospitalized patients taking oral rivaroxaban, who were diagnosed with NVAF and registered in the hospital information management system, were randomly assigned to a control group (n=100) and a study group (n=100) in a single-blind manner. The control group received pharmaceutical care based on the general pharmaceutical care model whereas the study group received care based on an evidence-based pharmaceutical care model. Patients’ satisfaction and cognition were evaluated regularly using questionnaires. The follow-up time was 1 year. We compared differences in satisfaction and cognition between the two groups after pharmaceutical-related care administered by clinical pharmacists.Results: The study group had higher satisfaction scores than the control group after the EBP intervention (14.58± 0.88 vs.13.81± 1.01, p< 0.01); cognition scores were also higher in the study group (22.58± 2.19 vs 20.80± 3.02, p< 0.01) after the intervention. In the study group, satisfaction was increased from a score of 10.15± 1.33 before the EBP intervention. Cognition also increased after the intervention in the study group, from a score of 9.88± 4.09 pre-intervention. In the control group, satisfaction was 10.04± 1.29 before the traditional pharmaceutical care intervention, smaller than the 13.81± 1.01 after the intervention (p< 0.01). Cognition in the control group was 9.83± 3.51 before traditional pharmaceutical care, smaller than the 20.80± 3.02 after the intervention (p< 0.01).Conclusion: The care model based on evidence-based pharmacy care can improve patient satisfaction and cognition, providing more comprehensive safety and efficacy of subsequent medication.Keywords: clinical pharmacist, evidence-based pharmacy, non-valvular atrial fibrillation, rivaroxaban, satisfaction, cognition
