Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring (Dec 2019)
Progress update from the hippocampal subfields group
- Rosanna K. Olsen,
- Valerie A. Carr,
- Ana M. Daugherty,
- Renaud La Joie,
- Robert S.C. Amaral,
- Katrin Amunts,
- Jean C. Augustinack,
- Arnold Bakker,
- Andrew R. Bender,
- David Berron,
- Marina Boccardi,
- Martina Bocchetta,
- Alison C. Burggren,
- M. Mallar Chakravarty,
- Gaël Chételat,
- Robin deFlores,
- Jordan DeKraker,
- Song‐Lin Ding,
- Mirjam I. Geerlings,
- Yushan Huang,
- Ricardo Insausti,
- Elliott G. Johnson,
- Prabesh Kanel,
- Olga Kedo,
- Kristen M. Kennedy,
- Attila Keresztes,
- Joshua K. Lee,
- Ulman Lindenberger,
- Susanne G. Mueller,
- Elizabeth M. Mulligan,
- Noa Ofen,
- Daniela J. Palombo,
- Lorenzo Pasquini,
- John Pluta,
- Naftali Raz,
- Karen M. Rodrigue,
- Margaret L. Schlichting,
- Yee Lee Shing,
- Craig E.L. Stark,
- Trevor A. Steve,
- Nanthia A. Suthana,
- Lei Wang,
- Markus Werkle‐Bergner,
- Paul A. Yushkevich,
- Qijing Yu,
- Laura E.M. Wisse,
- Hippocampal Subfields Group
Affiliations
- Rosanna K. Olsen
- Rotman Research Institute, Baycrest Health SciencesTorontoOntarioCanada
- Valerie A. Carr
- Department of PsychologySan Jose State UniversitySan JoseCAUSA
- Ana M. Daugherty
- Department of PsychologyWayne State UniversityDetroitMIUSA
- Renaud La Joie
- Department of NeurologyMemory and Aging Center, University of CaliforniaSan FranciscoCAUSA
- Robert S.C. Amaral
- Cerebral Imaging Centre, Douglas Hospital Mental Health University InstituteVerdunQuebecCanada
- Katrin Amunts
- C. and O. Vogt Institute for Brain ResearchMedical FacultyUniversity Hospital DüsseldorfDüsseldorfGermany
- Jean C. Augustinack
- Department of RadiologyHarvard Medical SchoolCharlestownMAUSA
- Arnold Bakker
- Department of Psychiatry and Behavioral SciencesJohns Hopkins University School of MedicineBaltimoreMDUSA
- Andrew R. Bender
- Department of Epidemiology and BiostatisticsMichigan State UniversityEast LansingMIUSA
- David Berron
- Clinical Memory Research UnitDepartment of Clinical Sciences MalmöLund UniversityLundSweden
- Marina Boccardi
- Department of PsychiatryUniversity of GenevaGenevaSwitzerland
- Martina Bocchetta
- Dementia Research CentreDepartment of Neurodegenerative DiseaseUniversity College LondonLondonUnited Kingdom
- Alison C. Burggren
- Robert and Beverly Lewis Center for Neuroimaging, University of OregonEugeneORUSA
- M. Mallar Chakravarty
- Cerebral Imaging Centre, Douglas Hospital Mental Health University InstituteVerdunQuebecCanada
- Gaël Chételat
- Université Normandie, Université de Caen‐NormandieCaenFrance
- Robin deFlores
- Université Normandie, Université de Caen‐NormandieCaenFrance
- Jordan DeKraker
- Robarts Research Institute, Brain and Mind Institute, University of Western OntarioLondonOntarioCanada
- Song‐Lin Ding
- Allen Institute for Brain ScienceSeattleWAUSA
- Mirjam I. Geerlings
- Julius Center for Health Sciences and Primary Care, University Medical Center UtrechtUtrechtThe Netherlands
- Yushan Huang
- Department of Biomedical EngineeringUniversity of AlbertaEdmontonAlbertaCanada
- Ricardo Insausti
- Human Neuroanatomy Laboratory, University of Castilla‐La ManchaAlbaceteSpain
- Elliott G. Johnson
- Center for Mind and Brain, University of CaliforniaDavisCAUSA
- Prabesh Kanel
- Department of Radiology at the University of MichiganAnn ArborMIUSA
- Olga Kedo
- Heinrich Heine University DüsseldorfDüsseldorfGermany
- Kristen M. Kennedy
- Center for Vital LongevityBehavioral and Brain ScienceThe University of Texas at DallasDallasTXUSA
- Attila Keresztes
- Center for Lifespan Psychology, Max Planck Institute for Human DevelopmentBerlinGermany
- Joshua K. Lee
- Department of Psychiatry and Behavioral SciencesUniversity of California Davis School of MedicineDavisCAUSA
- Ulman Lindenberger
- Research Centre for Natural Sciences, Hungarian Academy of SciencesBudapestHungary
- Susanne G. Mueller
- Department of RadiologyUniversity of CaliforniaSan FranciscoCAUSA
- Elizabeth M. Mulligan
- Department of PsychologyFlorida State UniversityTallahasseeFLUSA
- Noa Ofen
- Department of PsychologyWayne State UniversityDetroitMIUSA
- Daniela J. Palombo
- Department of PsychologyUniversity of British ColumbiaVancouverBritish ColumbiaCanada
- Lorenzo Pasquini
- Department of NeurologyMemory and Aging Center, University of CaliforniaSan FranciscoCAUSA
- John Pluta
- Division of Translational Medicine and GenomicsUniversity of PennsylvaniaPhiladelphiaPAUSA
- Naftali Raz
- Department of PsychologyWayne State UniversityDetroitMIUSA
- Karen M. Rodrigue
- Center for Vital LongevityBehavioral and Brain ScienceThe University of Texas at DallasDallasTXUSA
- Margaret L. Schlichting
- Department of PsychologyUniversity of TorontoTorontoOntarioCanada
- Yee Lee Shing
- Center for Lifespan Psychology, Max Planck Institute for Human DevelopmentBerlinGermany
- Craig E.L. Stark
- Department of Neurobiology and BehaviorCenter for Learning and Memory, University of CaliforniaIrvineCAUSA
- Trevor A. Steve
- Division of Neurology, Department of MedicineUniversity of AlbertaEdmontonAlbertaCanada
- Nanthia A. Suthana
- Department of Psychiatry and Biobehavioral Sciences, Department of NeurosurgeryUniversity of CaliforniaLos AngelesCAUSA
- Lei Wang
- Department of Psychiatry and Behavioral Sciences and Department RadiologyNorthwestern University Feinberg School of MedicineChicagoILUSA
- Markus Werkle‐Bergner
- Center for Lifespan Psychology, Max Planck Institute for Human DevelopmentBerlinGermany
- Paul A. Yushkevich
- Department of RadiologyUniversity of PennsylvaniaPhiladelphiaPAUSA
- Qijing Yu
- Department of PsychologyWayne State UniversityDetroitMIUSA
- Laura E.M. Wisse
- Department of RadiologyUniversity of PennsylvaniaPhiladelphiaPAUSA
- Hippocampal Subfields Group
- Rotman Research Institute, Baycrest Health SciencesTorontoOntarioCanada
- DOI
- https://doi.org/10.1016/j.dadm.2019.04.001
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 439 – 449
Abstract
Abstract Introduction Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence. Methods Our international working group, funded by the EU Joint Programme–Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption. Results This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures. Discussion A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.
Keywords
