Vascular Biology (Oct 2019)

Environmental stress influences mitochondrial metabolism in vascular cells: consequences for angiogenesis

  • T Scott Bowen,
  • Stuart Egginton

Journal volume & issue
Vol. 1, no. 1
pp. H111 – H116


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While the important and varied roles that vascular cells play in both health and disease is well recognised, the focus on potential therapeutic targets continually shifts as new players emerge. Here, we outline how mitochondria may be viewed as more than simply energy-generating organelles, but instead as important sentinels of metabolic health and effectors of appropriate responses to physiological challenges.