Sudan Journal of Medical Sciences (Dec 2018)

Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan

  • Najem Aldin Mohammed Osman,
  • Intisar Elhag Elraya,
  • Yassir Mahgoub Mohamed,
  • Muataz Mohamed Eldirdery,
  • Salaheldein Gumaa Elzaki,
  • Abdallah Elssir Ahmed,
  • and Ali Mohamed Elhassan Eleragi

DOI
https://doi.org/10.18502/sjms.v13i4.3596
Journal volume & issue
Vol. 2017
pp. 1 – 11

Abstract

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Background: Methicillin-resistant Staphylococcus aureus (MRSA) have emerged as an important cause of nosocomial and community-acquired infections ranging from mild to severe life-threatening infections. Therefore, a reliable detection of such strains is required for effective treatment. Objectives: To determine the frequency and the antibiogram of MRSA among different clinical isolates. Study Design: A cross-sectional, descriptive study. Materials and Methods: Standard bacteriological methods, disk diffusion and PCR were performed to determine the frequency of MRSA among different clinical isolates. Results: The overall results showed 96/210 (45.7%) of isolates were MRSA mostly recovered from wounds and blood stream. High percentage was detected in hospital-associated (HA) strains (64.2%) rather than community (CA) (37.1%) (P-value < 0.001). From the generated Antibiogram, Co-trimoxazole was the most active (80.2%), while Penicillin was the least one (6.2%). Conclusion: As MRSA strains were mostly isolated from Hospitals, clinicians should be aware of such burden strains. Local frequency investigation of MRSA is recommended for perfect diagnosis and treatment.

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