Nature Communications (Apr 2018)

De novo main-chain modeling for EM maps using MAINMAST

  • Genki Terashi,
  • Daisuke Kihara

DOI
https://doi.org/10.1038/s41467-018-04053-7
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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Main-chain tracing remains a time-consuming task for medium resolution cryo-EM maps. Here the authors describe MAINMAST, a computational approach for building main-chain structure models of proteins from EM maps of 4-5 Å resolution that builds main-chain models of the protein by tracing local dense points in the density distribution.