Emerging Infectious Diseases (Nov 2024)

Mpox Hepatic and Pulmonary Lesions in HIV/Hepatitis B Virus Co-Infected Patient, France

  • Ruxandra Calin,
  • Claire Périllaud-Dubois,
  • Stéphane Marot,
  • Khaldoun Kerrou,
  • Gilles Peytavin,
  • Marwa Bachir,
  • Anne Laure Kirch,
  • Ludovic Lassel,
  • Vincent Fallet,
  • Joel Gozlan,
  • Jean Baptiste Pain,
  • Patricia Senet,
  • Olivier Ferraris,
  • Sébastien Bine,
  • Mathieu Hubert,
  • Olivier Schwartz,
  • Laurence Morand-Joubert,
  • Gilles Pialoux

DOI
https://doi.org/10.3201/eid3011.241331
Journal volume & issue
Vol. 30, no. 11
pp. 2445 – 2447

Abstract

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We report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had <200 CD4+ cells/mm3, pulmonary and hepatic necrotic lesions, persistent viremia, and nasopharyngeal excretion. Clinical outcome was favorable after 90 days of tecovirimat treatment and administration of human vaccinia immunoglobulins.

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