Comparison of three exercise training method on plasma CRP levels and WBC in patients with type II diabetes

Abstract

Purpose Diabetes is a disease that causes a decrease in the function of the immune system of the body against infections.One of the inflammatory mediators, secreted along the white corpuscles after the interactions of inflammation, is CRP,which is a sensitive marker for systemic inflammation. Regular exercise with controlling metabolism in diabetes controlsthe blood glucose level and subsequently increases the immune response of body. For this purpose, this study has beendesigned to compare three different ways of training on CRP and WBC levels in type 2 diabetic patients. Methods: 52patients with type 2 diabetes (40-65 years old) were randomly divided into four groups: aerobic training, resistance,combined (aerobic and resistance) and control groups and each group consisted of 13 subjects. The exercises were done 3times a week for 60 minutes each session and lasted for 10 weeks. The WBC counts and high-sensitivity CRP (hs-CRP) atbaseline and at the end of the study were measured by ELISA. Results: The research findings showed significantreduction in hs-CRP and increased MONO, aerobic exercise group and decrease in CRP and NEUT levels and increase inMONO and LYM were seen in the combination group. CRP in the combination group was significantly higher thanaerobic alone, but no difference in WBC groups was noticed. Conclusions: According to the findings, the researchprescribes aerobic exercise training can be a particularly suitable compound to prevent complications of type 2 diabetes.

Keywords

• c-reactive protein
• white blood cell
• exercise training
• type 2 diabetes