Prognostic Value Determination of Sensitization to Lipid Transport Proteins in Patients with Seasonal Allergic Rhinitis

Abstract

Background of combination of seasonal allergic rhinitis (SAR) with cross food allergy (CFA) is confirmed by statistics. CFA is characterized by cross-reactions with SAR. Crossed reactions between food allergens and pollen are caused by common antigenic determinants contained in these allergens. Severity of crossed allergic reactions to fruits is caused by availability of sensitization to proteins PR-10, profilins and lipid transport proteins (LTP). The aim of this study is the evaluation of sensitization rate to LTP in patients with food allergy. Methods and results. 115 patients with sensitization to tree pollen and CFA were examined by methods of molecular allergodiagnostic. It was found that 11,1% of patients with sensitization to tree pollen with CFA have sensitization to LTP. Conclusion. This suggests that the early detection of sensitization to LTP is very important for prevention of severe systemic reactions and timely appointment of an elimination diet.

Keywords

• Seasonal Allergic Rhinitis
• Food Allergy
• Molecular Diagnostics
• Carrier Proteins