Analytical Cellular Pathology (Jan 2013)
Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
Abstract
Background: Chromosomal aneuploidy has been identified as a prognostic factor in the majority of sporadic carcinomas. However, it is not known how chromosomal aneuploidy affects chromosome-specific protein expression in particular, and the cellular proteome equilibrium in general.