CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease

• Lino Doering,
• Alex Cornean,
• Thomas Thumberger,
• Joergen Benjaminsen,
• Beate Wittbrodt,
• Tanja Kellner,
• Omar T. Hammouda,
• Matthias Gorenflo,
• Joachim Wittbrodt,
• Jakob Gierten

Affiliations

Lino Doering

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Alex Cornean

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Thomas Thumberger

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Joergen Benjaminsen

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Beate Wittbrodt

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Tanja Kellner

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Omar T. Hammouda

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Matthias Gorenflo

Department of Pediatric Cardiology, University Hospital Heidelberg, 69120 Heidelberg, Germany

Joachim Wittbrodt

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany

Jakob Gierten

Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany