Dissecting the role of the human microbiome in COVID-19 via metagenome-assembled genomes

Shanlin Ke; Scott T. Weiss; Yang-Yu Liu

doi:10.1038/s41467-022-32991-w

Nature Communications (Sep 2022)

Dissecting the role of the human microbiome in COVID-19 via metagenome-assembled genomes

Shanlin Ke,
Scott T. Weiss,
Yang-Yu Liu

Affiliations

Shanlin Ke: Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
Scott T. Weiss: Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
Yang-Yu Liu: Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School

DOI: https://doi.org/10.1038/s41467-022-32991-w
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 15

Abstract

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Here, using whole-metagenome shotgun sequencing data from patients with COVID-19 and controls, the authors reconstruct 11,584 microbial metagenome-assembled genomes (MAGs) including 5,403 non-redundant MAGs, revealing microbiota and metabolic pathways associations with SARS-CoV-2 infection at strain-level resolution.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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