Zhongliu Fangzhi Yanjiu (Apr 2023)

Progress in Development of Targeted Therapeutic Drugs for Acute Myeloid Leukemia

  • JI Xiaojun,
  • ZHAO Tingli,
  • MIAO Lei,
  • SI Yaxuan,
  • WU Jian,
  • XU Dan

DOI
https://doi.org/10.3971/j.issn.1000-8578.2023.22.1056
Journal volume & issue
Vol. 50, no. 4
pp. 413 – 421

Abstract

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Targeted therapeutic drugs for acute myeloid leukemia (AML) are showing immense development, thereby laying a solid foundation for the precise treatment of AML patients. The paper reviews four types of targeted drugs that have progressed rapidly for AML treatment (by targeting genes or signaling-pathway alterations, targeting apoptosis-related pathways, targeting cell-surface antigens, and targeting immune-related substances). We look forward to the future development directions of targeted drugs, providing references for hematologists and developers of new drugs for AML.

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