An unprecedented outbreak of pneumonia in Wuhan City, Hubei province in China emerged in December of 2019. COVID-19 is a betacoronavirus which consisted of a single-stranded ribonucleic acid (RNA) structure that belongs to the Coronavirinae subfamily. With respect to the large number of infected people that were exposed to the alive animals (bats, snakes, pangolins) in Wuhan City, China, it is suggested that this is likely the onset of a origin of COVID-19. The extensive functions have been carried out to reduce person-to-person transmission of COVID-19. In this review, the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease have been presented.