Associations of Polyp Characteristics in Children and Adolescents Presenting with Less Than Five Colorectal Polyps: A Full Colonoscopy Is Still Required
Ju Young Kim,
Yu Bin Kim,
Sujin Choi,
Yoo Min Lee,
Hyun Jin Kim,
Soon Chul Kim,
Hyo-Jeong Jang,
So Yoon Choi,
Dae Yong Yi,
Yoon Lee,
You Jin Choi,
Yunkoo Kang,
Kyung Jae Lee,
Suk Jin Hong,
Jun Hyun Hwang,
Sanggyu Kwak,
Byung-Ho Choe,
Ben Kang
Affiliations
Ju Young Kim
Department of Pediatrics, Daejeon Eulji Medical Center, Eulji University, Daejeon, Korea
Yu Bin Kim
Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea
Sujin Choi
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea
Yoo Min Lee
Department of Pediatrics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
Hyun Jin Kim
Department of Pediatrics, Chungnam National University Hospital, Daejeon, Korea
Soon Chul Kim
Department of Pediatrics, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Korea
Hyo-Jeong Jang
Department of Pediatrics, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea
So Yoon Choi
Department of Pediatrics, Kosin University Gospel Hospital, Kosin University College of Medicine, Busan, Korea
Dae Yong Yi
Department of Pediatrics, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea
Yoon Lee
Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea
You Jin Choi
Department of Pediatrics, Inje University Ilsan Paik Hospital, Goyang, Korea
Yunkoo Kang
Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju, Korea
Kyung Jae Lee
Department of Pediatrics, Hallym University College of Medicine, Chuncheon, Korea
Suk Jin Hong
Departments of Pediatrics, Daegu Catholic University School of Medicine, Daegu, Korea
Jun Hyun Hwang
Departments of Preventive Medicine, Daegu Catholic University School of Medicine, Daegu, Korea
Sanggyu Kwak
Departments of Medical Statistics, Daegu Catholic University School of Medicine, Daegu, Korea
Byung-Ho Choe
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea
Ben Kang
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea
Background/Aims: A full colonoscopy is currently required in children and adolescents with colorectal polyps, because of their potential of neoplastic transformation and complications such as intussusception. We aimed to analyze the associations of polyp characteristics in children and adolescents with colorectal polyps. Based on these findings, we also aimed to reevaluate the necessity of conducting a full colonoscopy. Methods: Pediatric patients <18 years of age who had undergone a colonoscopic polypectomy and those with <5 colorectal polyps were included in this multicenter, retrospective study. Baseline clinicodemographics, colonoscopic and histologic findings were investigated. Results: A total of 91 patients were included. Multivariate logistic regression analysis showed that polyp size was the only factor associated with the presence of any polyps located proximal to the splenic flexure (odds ratio [OR], 2.25; 95% confidence interval [CI], 1.28 to 4.28; p=0.007). Furthermore, polyp location proximal to the splenic flexure and sessile morphology were associated with the presence of any adenomatous polyp (OR, 8.51; 95% CI, 1.43 to 68.65; p=0.023; OR, 18.41; 95% CI, 3.45 to 173.81; p=0.002, respectively). Conclusions: In children and adolescents presenting with <5 colorectal polyps, polyp size and the presence of any adenomatous polyp were positively associated with polyp location proximal to the splenic flexure. This finding supports the necessity of a full colonoscopic exam in pediatric patients with colorectal polyps for the detection of polyps before the occurrence of complications such as intussusception or neoplastic transformation.
