Communications Biology (Aug 2022)

Chromatin compaction precedes apoptosis in developing neurons

  • Renata Rose,
  • Nicolas Peschke,
  • Elena Nigi,
  • Márton Gelléri,
  • Sandra Ritz,
  • Christoph Cremer,
  • Heiko J. Luhmann,
  • Anne Sinning

DOI
https://doi.org/10.1038/s42003-022-03704-2
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 18

Abstract

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Single-molecule imaging in developing cortical neurons shows that chromatin compaction precedes apoptosis and is an essential part of it, but can be uncoupled from the following apoptotic process.