Postoperative atypical hemolytic uremic syndrome in nontransplant setting: A case report with review of literature

Abstract

Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity. The proposed underlying mechanism is complement cascade dysregulation. aHUS has high morbidity and mortality. Prompt intervention with early initiation of therapeutic plasma exchange helps in the hematological remission thus reducing morbidity.

Keywords

• Atypical hemolytic uremic syndrome
• complement dysregulation
• postoperative
• therapeutic plasma exchange