Mediterranean Journal of Hematology and Infectious Diseases (Aug 2014)

Clinical complications in outpatient myelodysplastic syndromes

  • andrea tendas,
  • pasquale niscola,
  • luca cupelli,
  • laura scaramucci,
  • marco giovannini,
  • daniela piccioni,
  • teresa dentamaro,
  • alessio pio perrotti,
  • paolo de fabritiis

Journal volume & issue
Vol. 1

Abstract

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The outcome of myelodysplastic syndromes (MDS) depends on both progression to acute leukemia and complications development. During a 18-months observation period, non-toxic complications emerging in 48 outpatient MDS, of which 15 (31%) on active treatment and 33 (69%) receiving supportive measures alone, were recorded and analyzed. Out of 48 patients (median age of 72 years), 34 (71%) experienced complications; a total number of 92 events were recorded; most frequently observed events were infectious (38 events). Complications are a frequent issue in MDS; preventive measures should be increased and directed toward the most frequently observed complications.

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