Mediterranean Journal of Hematology and Infectious Diseases (Aug 2014)
Clinical complications in outpatient myelodysplastic syndromes
Abstract
The outcome of myelodysplastic syndromes (MDS) depends on both progression to acute leukemia and complications development. During a 18-months observation period, non-toxic complications emerging in 48 outpatient MDS, of which 15 (31%) on active treatment and 33 (69%) receiving supportive measures alone, were recorded and analyzed. Out of 48 patients (median age of 72 years), 34 (71%) experienced complications; a total number of 92 events were recorded; most frequently observed events were infectious (38 events). Complications are a frequent issue in MDS; preventive measures should be increased and directed toward the most frequently observed complications.