Disseminated herpes simplex virus 2 as a complication of pregnancy
Lauren Bougioukas,
Rachel B.C. Psoinos,
David C. Jones,
Erin A. Morris,
Andrew J. Hale
Affiliations
Lauren Bougioukas
Larner College of Medicine, University of Vermont, Burlington, VT, United States
Rachel B.C. Psoinos
Larner College of Medicine, University of Vermont, Burlington, VT, United States; University of Vermont Medical Center, United States
David C. Jones
Larner College of Medicine, University of Vermont, Burlington, VT, United States; University of Vermont Medical Center, United States; Fetal Diagnostic Center, United States
Erin A. Morris
Larner College of Medicine, University of Vermont, Burlington, VT, United States; University of Vermont Medical Center, United States
Andrew J. Hale
Larner College of Medicine, University of Vermont, Burlington, VT, United States; University of Vermont Medical Center, United States; Corresponding author at: University of Vermont Medical Center, Infectious Disease Unit, 111 Colchester Avenue, Mailstop 115 SM2, Burlington, VT, 05401, United States.
Disseminated herpes simplex virus 2 (HSV-2) infection, is a rare but devastating infection in pregnancy women. We present the case of a 30-year-old gravida 3, para 2−0-0−2, at 26 weeks 2 days gestation who presented with eleven days of vague and indolent symptoms before a diagnosis of disseminated HSV-2 infection with associated hepatitis was made. While the patient clinically improved with empiric acyclovir treatment, possibility of significant harm to the fetus remained, and the patient request elective termination. The authors review the epidemiology, diagnosis, treatment, and prognosis of disseminated HSV-2 infection in pregnancy.
