Synthesis of graphene quantum dots and their applications in drug delivery

Changhong Zhao; Xuebin Song; Ya Liu; Yifeng Fu; Lilei Ye; Nan Wang; Fan Wang; Lu Li; Mohsen Mohammadniaei; Ming Zhang; Qiqing Zhang; Johan Liu

doi:10.1186/s12951-020-00698-z

Journal of Nanobiotechnology (Oct 2020)

Synthesis of graphene quantum dots and their applications in drug delivery

Changhong Zhao,
Xuebin Song,
Ya Liu,
Yifeng Fu,
Lilei Ye,
Nan Wang,
Fan Wang,
Lu Li,
Mohsen Mohammadniaei,
Ming Zhang,
Qiqing Zhang,
Johan Liu

Affiliations

Changhong Zhao: School of Life Sciences and Technology, Xinxiang Medical University
Xuebin Song: School of Life Sciences and Technology, Xinxiang Medical University
Ya Liu: Electronics Materials and Systems Laboratory, Department of Microtechnology and Nanoscience, Chalmers University of Technology
Yifeng Fu: Electronics Materials and Systems Laboratory, Department of Microtechnology and Nanoscience, Chalmers University of Technology
Lilei Ye: SHT Smart High-Tech AB
Nan Wang: SHT Smart High-Tech AB
Fan Wang: School of Life Sciences and Technology, Xinxiang Medical University
Lu Li: School of Life Sciences and Technology, Xinxiang Medical University
Mohsen Mohammadniaei: Department of Health Technology, Technical University of Denmark
Ming Zhang: Department of Health Technology, Technical University of Denmark
Qiqing Zhang: School of Life Sciences and Technology, Xinxiang Medical University
Johan Liu: Electronics Materials and Systems Laboratory, Department of Microtechnology and Nanoscience, Chalmers University of Technology

DOI: https://doi.org/10.1186/s12951-020-00698-z
Journal volume & issue: Vol. 18, no. 1
pp. 1 – 32

Abstract

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Abstract This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.

Published in Journal of Nanobiotechnology

ISSN: 1477-3155 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Technology: Chemical technology: Biotechnology; Medicine: Medicine (General): Medical technology
Website: https://jnanobiotechnology.biomedcentral.com/

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Abstract

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