CLINICAL AND MORPHOLOGICAL MANIFESTATIONS OF TUBERCULOSIS IN PATIENTS WITH LATE-STAGE HIV INFECTION

Abstract

Clinical, X-ray, and bacteriological analyses versus a morphological examination of the following organs: meninges, lung, liver, spleen, adrenal glands, pancreas, heart, and mesenteric lymph nodes in 29 deceased patients with respiratory tuberculosis concurrent with HIV infection of mainly stages 4C and 5 show the particular severity of tuberculosis, a tendency towards a generalized process involving the majority of vital organs, morphologically characterized principally by an exudative and necrotic process with a preponderance of leukocyte infiltration without a tendency towards productive inflammation.This all causes death in patients. To improve the prognosis of tuberculosis in HIV-infected people, there is a need for the timely diagnosis of tuberculosis at HIV centers, antituberculosis therapy, and, if indicated, chemoprophylaxis.

Keywords

• туберкулез
• вич-инфекция
• морфологическое исследование
• больные