Nature Communications (Mar 2021)
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2
- Marie-Ming Aynaud,
- J. Javier Hernandez,
- Seda Barutcu,
- Ulrich Braunschweig,
- Kin Chan,
- Joel D. Pearson,
- Daniel Trcka,
- Suzanna L. Prosser,
- Jaeyoun Kim,
- Miriam Barrios-Rodiles,
- Mark Jen,
- Siyuan Song,
- Jess Shen,
- Christine Bruce,
- Bryn Hazlett,
- Susan Poutanen,
- Liliana Attisano,
- Rod Bremner,
- Benjamin J. Blencowe,
- Tony Mazzulli,
- Hong Han,
- Laurence Pelletier,
- Jeffrey L. Wrana
Affiliations
- Marie-Ming Aynaud
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- J. Javier Hernandez
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Seda Barutcu
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Ulrich Braunschweig
- Donnelly Centre for Cellular and Biomolecular Research, University of Toronto
- Kin Chan
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Joel D. Pearson
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Daniel Trcka
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Suzanna L. Prosser
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Jaeyoun Kim
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Miriam Barrios-Rodiles
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Mark Jen
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Siyuan Song
- Donnelly Centre for Cellular and Biomolecular Research, University of Toronto
- Jess Shen
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Christine Bruce
- Department of Microbiology, Mount Sinai Hospital/University Health Network
- Bryn Hazlett
- Department of Microbiology, Mount Sinai Hospital/University Health Network
- Susan Poutanen
- Department of Microbiology, Mount Sinai Hospital/University Health Network
- Liliana Attisano
- Donnelly Centre for Cellular and Biomolecular Research, University of Toronto
- Rod Bremner
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Benjamin J. Blencowe
- Donnelly Centre for Cellular and Biomolecular Research, University of Toronto
- Tony Mazzulli
- Department of Microbiology, Mount Sinai Hospital/University Health Network
- Hong Han
- Donnelly Centre for Cellular and Biomolecular Research, University of Toronto
- Laurence Pelletier
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- Jeffrey L. Wrana
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
- DOI
- https://doi.org/10.1038/s41467-021-21653-y
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Wide-spread outbreaks of pathogens require high intensity testing to manage. Here, the authors present C19-SPAR-Seq, a scalable and automated platform to analyse tens of thousands of SARS-CoV-2 patient samples in a single run.
