The transcription factor ZIP-1 promotes resistance to intracellular infection in Caenorhabditis elegans

Vladimir Lažetić; Fengting Wu; Lianne B. Cohen; Kirthi C. Reddy; Ya-Ting Chang; Spencer S. Gang; Gira Bhabha; Emily R. Troemel

doi:10.1038/s41467-021-27621-w

Nature Communications (Jan 2022)

The transcription factor ZIP-1 promotes resistance to intracellular infection in Caenorhabditis elegans

Vladimir Lažetić,
Fengting Wu,
Lianne B. Cohen,
Kirthi C. Reddy,
Ya-Ting Chang,
Spencer S. Gang,
Gira Bhabha,
Emily R. Troemel

Affiliations

Vladimir Lažetić: Division of Biological Sciences, University of California
Fengting Wu: Division of Biological Sciences, University of California
Lianne B. Cohen: Division of Biological Sciences, University of California
Kirthi C. Reddy: Division of Biological Sciences, University of California
Ya-Ting Chang: Department of Cell Biology, New York University School of Medicine
Spencer S. Gang: Division of Biological Sciences, University of California
Gira Bhabha: Department of Cell Biology, New York University School of Medicine
Emily R. Troemel: Division of Biological Sciences, University of California

DOI: https://doi.org/10.1038/s41467-021-27621-w
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 16

Abstract

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Intestinal immune responses to intracellular infection of Caenorhabditis elegans and other Invertebrate hosts are not well understood. Here the authors show a key role for the transcription factor ZIP-1 during intestinal intracellular infection.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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