BMC Cardiovascular Disorders (Jan 2009)

Characteristics of acute congestive heart failure with normal ejection fraction and less elevated B-type natriuretic peptide

  • Sakai Akiko,
  • Kasai Yufuko,
  • Honma Miho,
  • Mizuochi Kiyoko,
  • Koike Natsuha,
  • Shimamoto Ken,
  • Fujita Etsuko,
  • Kawana Masatoshi

DOI
https://doi.org/10.1186/1471-2261-9-2
Journal volume & issue
Vol. 9, no. 1
p. 2

Abstract

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Abstract Background Heterogeneity in B-type natriuretic peptide (BNP) levels, especially among individuals with acute heart failure with normal left ventricular ejection fraction (HFNEF), can cause confusion in interpreting results. We investigated the characteristics of cases of acute HFNEF with only modestly elevated BNP. Methods One hundred forty-two patients with acute or acute exacerbation of chronic HFNEF were divided into two groups by BNP level: BNP Results In the NB group, a history of open-heart surgery (OHS) was more frequent (71% vs. 22%, p Conclusion We found associations between acute HFNEF with less elevated BNP and a history of OHS. In a patient suspected of HFNEF, a history of OHS is considered diagnostic evidence of presence of diastolic heart failure when plasma levels of BNP are less elevated.