Deciphering relationship between microhomology and in-frame mutation occurrence in human CRISPR-based gene knockout

• Guohui Chuai,
• Fayu Yang,
• Jifang Yan,
• Yanan Chen,
• Qin Ma,
• Chi Zhou,
• Chenyu Zhu,
• Feng Gu,
• Qi Liu

Affiliations

Guohui Chuai

Department of Central Laboratory, Shanghai Tenth People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

Fayu Yang

School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Zhejiang, China

Jifang Yan

Department of Central Laboratory, Shanghai Tenth People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

Yanan Chen

Department of Central Laboratory, Shanghai Tenth People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

Qin Ma

Department of Plant Science, BioSNTR, South Dakota State University, Brookings, South Dakota, USA

Chi Zhou

Department of Central Laboratory, Shanghai Tenth People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

Chenyu Zhu

Department of Central Laboratory, Shanghai Tenth People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

Feng Gu

School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Zhejiang, China

Qi Liu

Department of Central Laboratory, Shanghai Tenth People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China