Recent Progresses in NIR-II Luminescent Bio/Chemo Sensors Based on Lanthanide Nanocrystals
Tingyu Yang,
Jinglei Qin,
Jinling Zhang,
Lanying Guo,
Mu Yang,
Xi Wu,
Mei You,
Hongshang Peng
Affiliations
Tingyu Yang
College of Life and Environmental Science, Minzu University of China, Beijing 100081, China
Jinglei Qin
Key Laboratory of Luminescence and Optical Information, Ministry of Education, Institute of Optoelectronic Technology, Beijing Jiaotong University, Beijing 100044, China
Jinling Zhang
College of Life and Environmental Science, Minzu University of China, Beijing 100081, China
Lanying Guo
School of Medical Imaging, Wannan Medical College, Wuhu 241002, China
Mu Yang
Key Laboratory of Luminescence and Optical Information, Ministry of Education, Institute of Optoelectronic Technology, Beijing Jiaotong University, Beijing 100044, China
Xi Wu
College of Science, Minzu University of China, Beijing 100081, China
Mei You
College of Science, Minzu University of China, Beijing 100081, China
Hongshang Peng
College of Science, Minzu University of China, Beijing 100081, China
Fluorescent bio/chemosensors are widely used in the field of biological research and medical diagnosis, with the advantages of non-invasiveness, high sensitivity, and good selectivity. In particular, luminescent bio/chemosensors, based on lanthanide nanocrystals (LnNCs) with a second near-infrared (NIR-II) emission, have attracted much attention, owing to greater penetration depth, aside from the merits of narrow emission band, abundant emission lines, and long lifetimes. In this review, NIR-II LnNCs-based bio/chemo sensors are summarized from the perspectives of the mechanisms of NIR-II luminescence, synthesis method of LnNCs, strategy of luminescence enhancement, sensing mechanism, and targeted bio/chemo category. Finally, the problems that exist in present LnNCs-based bio/chemosensors are discussed, and the future development trend is prospected.
