Medisur (Feb 2019)
Clinical and cytopathological diagnosis of oral herpes simplex in patients with kidney transplant
Abstract
Foundation: the use of medications potentially inmunodepressors has allowed an improvement in the longer and quality life in patients with renal transplant, but favor the deterioration of the immune system and the appearance of diverse opportunistic viral infections, among them herpes simplex, which is contagious and incurable and responsible of the starting of multiple lesions which affect the skin and mucose. Objective: to identify the clinical and cytopathological manifestations of oral lesions caused by the herpes simplex virus in patients with kidney transplant. Methods: a descriptive cross study, with a universe of 50 patients with renal transplant diagnosed clinically with a herpes infection, assisted in a dentistry consultation of the Polyclinic of Specialties at the Clinical Surgical University Hospital Saturnino Lora Torres, Santiago of Cuba, from November 2014 to the same the month 2016. For primary data collection a survey was designed including: age, sex, topographic location, clinical symptoms and lesion predisposing factors, so as present cellular disturbances in the oral epithelium. A cytopathological study of the lesions was performed. Results: the male sex and pain as a clinical symptom predominated, the most frequent location was the vermillon of the lower lip, the presence of giant epithelial multinucleated cells with bodies of intranuclear inclusions, and necrosis of infected cells, respectively, were the most important cytologic findings. Conclusion: in all of the patients there were oral lesions compatible with infection by the virus of herpes simplex.
