Thrombotic thrombocytopenic purpura and defective apoptosis due to CASP8/10 mutations: the role of mycophenolate mofetil

• F. Fioredda,
• E. Cappelli,
• A. Mariani,
• A. Beccaria,
• E. Palmisani,
• A. Grossi,
• I. Ceccherini,
• R. Venè,
• C. Micalizzi,
• M. Calvillo,
• F. Pierri,
• I. Mancini,
• F. Peyvandi,
• F. Corsolini,
• C. Dufour,
• M. Miano

Affiliations

F. Fioredda

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;; F. Fioredda, Unit of Haematology, IRCCS Istituto Giannina Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy

E. Cappelli

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

A. Mariani

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

A. Beccaria

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

E. Palmisani

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

A. Grossi

Medical Genetics Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

I. Ceccherini

Medical Genetics Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

R. Venè

Molecular Oncology and Angiogenesis Unit, IRCCS AOU San Martino–IST, Genoa, Italy;

C. Micalizzi

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

M. Calvillo

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

F. Pierri

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

I. Mancini

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Università degli Studi di Milano, Department of Pathophysiology and Transplantation and Fondazione Luigi Villa, Milan, Italy;

F. Peyvandi

Department of Pathophysiology and Transplantation, Università degli Studi di Milano and Fondazione Luigi Villa, Milan, Italy;; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

F. Corsolini

Laboratory of Molecular Genetics and Biobanks, IRCCS Istituto Giannina Gaslini, Genoa, Italy

C. Dufour

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;

M. Miano

Unit of Haematology, IRCCS Istituto Giannina Gaslini, Genoa, Italy;