The role of kidney biopsy in diagnosis of preeclampsia in kidney transplant patients

Abstract

Objective The aim of this report is to review two patients who developed proteinuria in pregnancy after kidney transplant in order to highlight the importance of maintaining a broad differential and the diagnostic utility of kidney biopsy in this clinical scenario. Methods Two cases of women with kidney transplants who presented with proteinuria in pregnancy are described and the literature is reviewed. Results In both cases, a kidney biopsy allowed for prompt diagnosis and treatment. Conclusion Kidney biopsy should be considered an important diagnostic tool in this clinical scenario. Abbreviations ACE: angiotensin-converting enzyme; ESKD: end-stage kidney disease; FSGS: focal segmental glomerulosclerosis; RAAS: renin aldosterone angiotensin system

Keywords

• preeclampsia
• pregnancy
• transplant