Data on the stability of Prx1-associated snRNAs and mRNAs
Eun-Kyung Kim,
Sung-Min Ahn,
Ho Hee Jang
Affiliations
Eun-Kyung Kim
Department of Biochemistry, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea
Sung-Min Ahn
Department of Genome Medicine and Science, College of Medicine, Gachon University, Incheon, 21936, Republic of Korea; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, 21565, Republic of Korea; Corresponding author. Department of Genome Medicine and Science, College of Medicine, Gachon University, Incheon, 21936, Republic of Korea.
Ho Hee Jang
Department of Biochemistry, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea; Department of Health Sciences and Technology, Graduate School of Medicine, Gachon University, Incheon, 21999, Republic of Korea; Corresponding author. Department of Biochemistry, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea.
This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SNU484 and HeLa cells, which were then treated with Actinomycin D (ActD) to inhibit transcription. After that, we measured the levels of Prx1-associated snRNAs and mRNAs using qPCR analysis. Keywords: Peroxiredoxin1, Small nuclear RNA, RNA stability, Protein-RNA interaction
