G3: Genes, Genomes, Genetics (Dec 2022)

Transcriptome-wide analysis of pseudouridylation in <i>Drosophila melanogaster</i>

  • Wan Song,
  • Ram Podicheti,
  • Douglas B Rusch,
  • William Daniel Tracey

DOI
https://doi.org/10.1093/g3journal/jkac333
Journal volume & issue
Vol. 13, no. 3

Abstract

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AbstractPseudouridine (Psi) is one of the most frequent post-transcriptional modification of RNA. Enzymatic Psi modification occurs on rRNA, snRNA, snoRNA, tRNA, and non-coding RNA and has recently been discovered on mRNA. Transcriptome-wide detection of Psi (Psi-seq) has yet to be performed for the widely studied model organism Drosophila melanogasterRluA-2w1118