Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab

• Wei Xu,
• Anna Spreafico,
• Stephanie Lheureux,
• Marcus O Butler,
• Aaron R Hansen,
• Eric Chen,
• Ben Wang,
• Philippe L Bedard,
• Albiruni Abdul Razak,
• Dave Cescon,
• Lillian L Siu,
• Tak W Mak,
• Geoffrey Alan Watson,
• Enrique Sanz-Garcia,
• Wen-Jiang Zhang,
• Zhihui Amy Liu,
• SY Cindy Yang,
• Shaofeng Liu,
• Shawn Kubli,
• Hal Berman,
• Thomas Pfister,
• Sofia Genta

Affiliations

Wei Xu

research student

Anna Spreafico

Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Stephanie Lheureux

Division of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Marcus O Butler

Princess Margaret Hospital Cancer Centre, Toronto, Ontario, Canada

Aaron R Hansen

6 Department of Medical Oncology, Princess Margaret Hospital Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada

Eric Chen

Department of Emergency Medicine, Henry Ford Health System, Detroit, Michigan, USA

Ben Wang

Immunology, University of Toronto, Toronto, Ontario, Canada

Philippe L Bedard

Department of Medicine, Division of Medical Oncology and Hematology, Princess Margaret Hospital Cancer Centre, Toronto, Ontario, Canada

Albiruni Abdul Razak

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Dave Cescon

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Lillian L Siu

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Tak W Mak

5Princess Margaret Cancer Centre, University Health Network, Canada

Geoffrey Alan Watson

Division of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Enrique Sanz-Garcia

Division of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Wen-Jiang Zhang

Division of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Zhihui Amy Liu

Biostatistics, Princess Margaret Hospital Cancer Centre, Toronto, Ontario, Canada

SY Cindy Yang

Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Shaofeng Liu

Immunology, University of Toronto, Toronto, Ontario, Canada

Shawn Kubli

Immunology, University of Toronto, Toronto, Ontario, Canada

Hal Berman

Laboratory Medicine and Pathobiology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Thomas Pfister

Laboratory Medicine and Pathobiology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Sofia Genta

Division of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada