Nature Communications (Aug 2018)
AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
- Marie-Christine Klein,
- Katharina Zimmermann,
- Stefan Schorr,
- Martina Landini,
- Patrick A. W. Klemens,
- Jacqueline Altensell,
- Martin Jung,
- Elmar Krause,
- Duy Nguyen,
- Volkhard Helms,
- Jens Rettig,
- Claudia Fecher-Trost,
- Adolfo Cavalié,
- Markus Hoth,
- Ivan Bogeski,
- H. Ekkehard Neuhaus,
- Richard Zimmermann,
- Sven Lang,
- Ilka Haferkamp
Affiliations
- Marie-Christine Klein
- Medical Biochemistry and Molecular Biology, Saarland University
- Katharina Zimmermann
- Biophysics, CIPMM Saarland University
- Stefan Schorr
- Medical Biochemistry and Molecular Biology, Saarland University
- Martina Landini
- Plant Physiology, Technical University Kaiserslautern
- Patrick A. W. Klemens
- Plant Physiology, Technical University Kaiserslautern
- Jacqueline Altensell
- Plant Physiology, Technical University Kaiserslautern
- Martin Jung
- Medical Biochemistry and Molecular Biology, Saarland University
- Elmar Krause
- Physiology, CIPMM Saarland University
- Duy Nguyen
- Center for Bioinformatics, Saarland University
- Volkhard Helms
- Center for Bioinformatics, Saarland University
- Jens Rettig
- Physiology, CIPMM Saarland University
- Claudia Fecher-Trost
- Experimental and Clinical Pharmacology and Toxicology, Saarland University
- Adolfo Cavalié
- Experimental and Clinical Pharmacology and Toxicology, Saarland University
- Markus Hoth
- Biophysics, CIPMM Saarland University
- Ivan Bogeski
- Biophysics, CIPMM Saarland University
- H. Ekkehard Neuhaus
- Plant Physiology, Technical University Kaiserslautern
- Richard Zimmermann
- Medical Biochemistry and Molecular Biology, Saarland University
- Sven Lang
- Medical Biochemistry and Molecular Biology, Saarland University
- Ilka Haferkamp
- Plant Physiology, Technical University Kaiserslautern
- DOI
- https://doi.org/10.1038/s41467-018-06003-9
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 14
Abstract
Endoplasmic reticulum (ER) functioning requires a constant supply of ATP, but the exchanger required for ATP uptake into the ER is unknown. Here, the authors report that SLC35B1, here named AXER, or ATP/ADP exchanger into the ER, can transport ATP into the ER.
