Revista Ciencias de la Salud (Dec 2006)

Biochemistry Applied to Everyday Life: Chemical Equilibrium and the Transporting Function of the Hemoglobin

  • Carlos Mario Echeverría Palacio,
  • Raúl Ramírez Grueso,
  • Kelly Coba Torres,
  • María Orfa Rojas†

Journal volume & issue
Vol. 4, no. 2
pp. 109 – 115

Abstract

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The hemoglobin is a blood protein which cantransport oxygen, a gas insoluble in water, todifferent organs where it is required for the properfunction; this protein also transports themetabolic products, CO2 and H+ for theirexcretion. This process depends on pH, the BPGconcentration, pO2 and pCO2. The cooperativebinding between hemoglobin and those compoundsand the conformational changes necessaryfor oxygen and CO2 uptake and release inthe specific place where they are required. Abruptchanges of atmospheric pressure associatedwith height and the exposure to other gases suchas CO present in vehicles and closed roomscould compromise the normal functioning of theorganism because their presence affects thetransport function of the hemoglobin. In thispaper, we will explain everyday phenomenarelated to the transport of gases through hemoglobinas a demonstration that a knowledge ofbiochemistry begins to be useful from now on to understand everyday situations and give usan expectation of their value to comprehendmany health problems that would be faced inthe future

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