Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer

Abstract

Given the serious threat of lung cancer due to the strong concealment at early stage, primary diagnosis becomes quite essential to guarantee human health. The adsorption behaviors of introduced Ir-CNT upon two categories of typical gases of lung cancer (aniline and o-toluidine) have been investigated based on DFT method. At the same time, the sensing characteristics towards these two gases were conducted as well by our prepared sensors prepared by drying the Ir deposited CNT aqueous solution onto the interdigital electrode substrate. Results indicate that Ir-CNT based material can be desirable and promising for sensing upon exhaled gas of lung cancer patient, because of the excellent adsorptions upon two kinds of main typical gases. Such strong interactions of Ir-CNT towards typical gas adsorbed leads to the significant electronic redistributions of the modified surface, thereby causing apparent reduction in conductivity after adsorptions. This could be detected by a practical prepared resistivity-type sensor. Our theoretical calculations are in good accordance with the experimental results, which demonstrate the feasibility of Ir-CNT for potential application in the near future in the field of lung cancer diagnosis.