A rare case of statin-induced quadriparesis: Electromyographic and histopathological correlation

Abstract

Statins play a vital role in the prevention of atherosclerotic cardiovascular complications and statin therapy continues to be cornerstone in treating patients with dyslipidemia. However, statin-associated myopathy affects up to 10%–12% of patients which can range from myalgia to a severe muscle weakness and rhabdomyolysis. Histopathological features and neuroimaging changes of statin-induced weakness are not studied so often. We present a case of 65-year-old female patient who presented with quadriparesis and myalgia-induced by statins; and we tried to find histopathological and electromyographic changes associated with statin-induced myopathy.

Keywords

• Electromyography
• histopathological examination
• quadriparesis
• statins