Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University; Anesthesiologist-Reanimatologist, Children's City Hospital named after G.K. Filippsky
Doctor of Medical Sciences, Associate Professor, Head of the of Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University; Deputy Chief Physician for Pediatric Care, Stavropol Regional Clinical Perinatal Center No. 1
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University; Deputy Chief Medical Officer, Shpakovskaya District Hospital
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University; Head of the Department of Anesthesiology and Intensive Care No. 1, Stavropol Regional Clinical Hospital
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Resuscitation with a Course of Additional Professional Education, Stavropol State Medical University; Head of the Department of Anesthesiology and Intensive Care No. 1, Stavropol City Clinical Emergency Hospital
A review of the literature on intensive care (IC) management of acute salicylate (SC) toxicity in children and adolescents was conducted. The information was gathered from the PubMed, Science Direct, and eLibrary databases using the keywords: "salicylates", "children", "adolescents", "acute poisoning", "overdose", and "intensive care." The review included sources published over the last 10 years (2014-2024). The criteria for including studies in the review were data regarding the pathogenesis, clinical manifestations, and specific features of IC for SC poisoning in children and adolescents. Works that focused exclusively on adult patients were excluded from the review. Although the drugs are known to be contraindicated in children, acute SC poisoning continues to be common in pediatric practice. The clinical manifestations are nonspecific and may include central nervous, gastrointestinal, and respiratory disturbances. Measuring plasma SC concentration is a crucial diagnostic test for assessing the severity of poisoning. The effectiveness of gastric lavage has not been proven, and adsorbents are only justified within the first two hours after exposure. Effective IC methods for SC poisoning include infusion therapy, urinary alkalinization using sodium bicarbonate, and extracorporeal treatment. With modern and adequate emergency care, the prognosis for recovery is considered favorable.
