Case report: complete long-lasting response to multimodal third line treatment with neurosurgical resection, carmustine wafer implantation and dabrafenib plus trametinib in a BRAFV600E mutated high-grade glioma

• Barbara Castelli,
• Marco Tellini,
• Melina Guidi,
• Marco Di Nicola,
• Laura Giunti,
• Anna Maria Buccoliero,
• Maria Luigia Censullo,
• Alessandro Iacono,
• Isacco Desideri,
• Lorenzo Genitori,
• Iacopo Sardi,
• Carla Fonte

Affiliations

Barbara Castelli

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Marco Tellini

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Melina Guidi

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Marco Di Nicola

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Laura Giunti

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Anna Maria Buccoliero

Pathology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Maria Luigia Censullo

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Alessandro Iacono

Radiology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Isacco Desideri

Radiotherapy Department, Careggi Hospital, Florence, Italy

Lorenzo Genitori

Neurosurgery Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Iacopo Sardi

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy

Carla Fonte

Neuro-oncology Department, Meyer Children’s Hospital IRCCS, Florence, Italy