PLoS ONE (Jan 2022)

Clinical usefulness of the pattern of non-adherence to anti-platelet regimen in stented patients (PARIS) thrombotic risk score to predict long-term all-cause mortality and heart failure hospitalization after percutaneous coronary intervention.

  • Joh Akama,
  • Takeshi Shimizu,
  • Takuya Ando,
  • Fumiya Anzai,
  • Yuuki Muto,
  • Yusuke Kimishima,
  • Takatoyo Kiko,
  • Akiomi Yoshihisa,
  • Takayoshi Yamaki,
  • Hiroyuki Kunii,
  • Kazuhiko Nakazato,
  • Takafumi Ishida,
  • Yasuchika Takeishi

DOI
https://doi.org/10.1371/journal.pone.0274287
Journal volume & issue
Vol. 17, no. 9
p. e0274287

Abstract

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BackgroundThe Patterns of non-Adherence to Anti-Platelet Regimen in Stented Patients (PARIS) thrombotic risk score has been proposed to estimate the risk of stent thrombotic events after percutaneous coronary intervention (PCI). However, the prognostic value of the PARIS thrombotic risk score for long term all-cause and cardiac mortalities, as well as hospitalization due to heart failure, has not yet been evaluated. Therefore, the aim of the present study was to evaluate the prognostic value of the PARIS thrombotic risk score for all-cause and cardiac mortalities and hospitalization due to heart failure following PCI.Methods and resultsConsecutive 1,061 patients who underwent PCI were divided into three groups based on PARIS thrombotic risk score; low- (n = 320), intermediate- (n = 469) and high-risk (n = 272) groups. We followed up on all three groups for all-cause mortality, cardiac mortality and hospitalization due to heart failure. Kaplan-Meier analysis showed that all outcomes were highest in the high-risk group (P ConclusionThe PARIS thrombotic risk score is a significant prognostic indicator for all-cause mortality and hospitalization due to heart failure in patients after PCI.