Computational and Structural Biotechnology Journal (Jan 2021)

K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases

  • Hongzhi Wang,
  • Zhiying Miao,
  • Chaobao Zhang,
  • Xiaona Wei,
  • Xiangqi Li

Journal volume & issue
Vol. 19
pp. 1966 – 1975

Abstract

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Infectious disease is a great enemy of humankind. The ravages of COVID-19 are leading to profound crises across the world. There is an urgent requirement for analyzing the current pandemic situation, predicting trends over time, and assessing the effectiveness of containment measures. Thus, numerous statistical models, primarily based on the susceptible–exposed–infected–recovered or removed (SEIR) model, have been established. However, these models are highly technical, which are difficult for the public and governing bodies to understand and use. To address this issue, we developed a simple operating software based on our improved K-SEIR model termed as the kernel SEIR simulator (K-SEIR-Sim). This software includes natural propagation parameters, containment measure parameters, and certain characteristic parameters that can deduce the effects of natural propagation and containment measures. Further, the applicability of the proposed software was demonstrated using the examples of the COVID-19 outbreak in the United States, Wuhan city of China, Diamond Princess, and France. Operating results verified the potency of the proposed software in evaluating the epidemic situation and human intervention during COVID-19. Importantly, no installation is required and the software can perform real-time, backward-looking, and forward-looking analysis by functioning in data-driven and model-driven ways. All of them have considerable practical values in their applications according to the actual needs of personal use. Conclusively, K-SEIR-Sim is the first simple customized operating software that is highly valuable for the global fight against COVID-19 and other infectious diseases.

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