PLoS ONE (Jan 2021)

Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France.

  • Camille d'Humières,
  • Juliette Patrier,
  • Brice Lortat-Jacob,
  • Alexy Tran-Dinh,
  • Lotfi Chemali,
  • Naouale Maataoui,
  • Emilie Rondinaud,
  • Etienne Ruppé,
  • Charles Burdet,
  • Stéphane Ruckly,
  • Philippe Montravers,
  • Jean-François Timsit,
  • Laurence Armand-Lefevre

DOI
https://doi.org/10.1371/journal.pone.0250728
Journal volume & issue
Vol. 16, no. 4
p. e0250728

Abstract

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Among 197 COVID-19 patients hospitalized in ICU, 88 (44.7%) experienced at least one bacterial infection, with pneumonia (39.1%) and bloodstream infections (15,7%) being the most frequent. Unusual findings include frequent suspicion of bacterial translocations originating from the digestive tract as well as bacterial persistence in the lungs despite adequate therapy.