Journal for ImmunoTherapy of Cancer (Nov 2023)
635 A phase 1, first in human (FIH) study of autologous macrophages engineered to express an anti-HER2 chimeric antigen receptor (CAR) in participants (pts) with HER2 overexpressing solid tumors
- Yuan Yuan,
- Michael Klichinsky,
- Saar Gill,
- Melissa Johnson,
- Thomas Condamine,
- Jennifer Specht,
- Richard T Maziarz,
- Kim Reiss,
- Debora Barton,
- Daniel Cushing,
- Joanne Mortimer,
- Paula R Pohlmann,
- E Claire Dees,
- Naoto Ueno,
- Mathew Angelos,
- Ramona F Swaby,
- Yara Abdou
Affiliations
- Yuan Yuan
- 8Cedars-Sinai, Los Angeles, CA, USA
- Michael Klichinsky
- Carisma Therapeutics, Philadelphia, PA, USA
- Saar Gill
- Aff125 grid.25879.310000000419368972Center for Cellular ImmunotherapiesUniversity of Pennsylvania Philadelphia PA USA
- Melissa Johnson
- 4Sarah Cannon Research Institute, Nashville, TN, USA
- Thomas Condamine
- 3Carisma Therapeutics, Philadelphia, PA, USA
- Jennifer Specht
- 2Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- Richard T Maziarz
- BMT & Cell Therapy Program, Division of Hematology/Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon, USA
- Kim Reiss
- 1University of Pennsylvania, Philadelphia, PA, USA
- Debora Barton
- 3Carisma Therapeutics, Springfield, NJ, USA
- Daniel Cushing
- Carisma Therapeutics, Philadelphia, PA, USA
- Joanne Mortimer
- 2City of Hope, Duarte, CA, USA
- Paula R Pohlmann
- 3The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- E Claire Dees
- 7University of North Carolina Lineberger Comprehensive Cancer, Chapel Hill, NC, USA
- Naoto Ueno
- 3The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Mathew Angelos
- 9University of Pennsylvania Abramson Cancer Center, Philadelphia, PA, USA
- Ramona F Swaby
- 10Carisma Therapeutics, Philadelphia, PA, USA
- Yara Abdou
- 12University of North Carolina at Chapel Hill, Durham, NC, USA
- DOI
- https://doi.org/10.1136/jitc-2023-SITC2023.0635
- Journal volume & issue
-
Vol. 11,
no. Suppl 1
Abstract
No abstracts available.