We present a procedure for exposure and vulnerability evaluation that integrates LiDAR, orthophotos, and other ancillary datasets. It comprises three phases: (1) city stratification into homogeneous regions; (2) exposure database compilation; and (3) vulnerability allocation using predictive modelling. We have conducted two applications in Lorca (Spain) and Port-au-Price (Haiti) and here we compare them. Each phase of the method is subject to variations due mainly to data availability; however, it does not affect the final accuracy that remains high in both scenarios (over 80%). It is a flexible procedure that is able to adapt to the particular features of two different cities.