Cognitive Impairment and Dementia Data Model: Quality Evaluation and Improvements

Abstract

Recently, datasets with various factors and indicators of cognitive diseases have been available for clinical research. Although the transformation of information to a particular data model is straightforward, many challenges arise if data from different repositories have to be integrated. Since each data source keeps entities with different names and relationships at different levels of granularity and format, the information can be partially lost or not properly presented. It is therefore important to have a common data model that provides a unified description of different factors and indicators related to cognitive diseases. Thus, in our previous work, we proposed a hierarchical cognitive impairment and dementia data model that keeps the semantics of the data in a human-readable format and accelerates the interoperability of clinical datasets. It defines data entities, their attributes and relationships related to diagnosis and treatment. This paper extends our previous work by evaluating and improving the data model by adapting the methodology proposed by D. Moody and G. Shanks. The completeness, simplicity, correctness and integrity of the data model are assessed and based on the results a new, improved version of the model is generated. The understandability of the improved model is evaluated using an online questionnaire. Simplicity and integrity are also considered as well as the factors that may influence the flexibility of the data model.

Keywords

• data modeling
• data model quality evaluation
• cognitive impairment
• dementia
• interoperability of clinical data