Nature Communications (Apr 2017)

Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution

  • Shaul Yogev,
  • Celine I. Maeder,
  • Roshni Cooper,
  • Mark Horowitz,
  • Adam G. Hendricks,
  • Kang Shen

DOI
https://doi.org/10.1038/ncomms15063
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 14

Abstract

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Microtubule dynamics are essential for axonal transport. InC. elegans, the authors show that dynein heavy chain regulates the spatial distribution of dendritic microtubules which ensures correct transport progression.