Vіsnik Naukovih Doslіdžen' (Apr 2018)
ANALYSIS OF DIFFERENT CELL TECHNOLOGIES USE IN PRACTICAL DENTISTRY
Abstract
The development of the modern implantology industry, which allows for the effective rehabilitation of dental patients in cases of partial and complete adentia, involves reducing the number of relative contraindications to the establishment of titanium intralesional structures, especially in cases of bone defect or insufficient geometric parameters of the residual crest. The aim of the study – to analyze the results of cell engineering principles use in dental practice based on data from clinical, laboratory and experimental studies published in scientific periodical journals, and justify the need for systematization of different approaches to improve the efficiency of such manipulations during the reconstruction activities in maxillofacial area. Materials and Methods. During the retrospective analysis of the literature 98 scientific publications were evaluated, of which 32 were represented in detailed manner as such that significantly differ or represent different qualitative approaches for reconstructive manipulation in dental practice. Primary data search was conducted using Google Scholar engine by keywords and formulation of search task based on individual words or phrases. The sample of relevant publications was formed using the method of content analysis, principles of which allowed us to systematize the results of research in the software Microsoft Excel 2013 (Microsoft Office, 2013). Results and Discussion. The analysis of the principles of cell engineering in dental practice according to the clinical, laboratory and experimental research data suggests the complexity of the systematization for such type of results due to the different methodological approaches, different valuation parameters for initial and final results, and different purposes of a regeneratory therapy, that were used in previous studies. Some studies evaluated the actual recovery of a certain bone volume, but others just confirm the presence of existing regenerative potential. Conclusions. Further development and modification of existing approaches for regenerative therapies with the use of third generation materials by Egusa (2012), enhances the effectiveness of various types of reconstructive surgery in maxillofacial area, and the lack of appropriate algorithms for stem cells management, their adequate collection and transfer remains questionable within regeneratory therapy in dental practice.
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