Research and Reports in Urology (Aug 2017)

Acotiamide hydrochloride hydrate added to combination treatment with an α-blocker and a cholinergic drug improved the QOL of women with acute urinary retention: case series

  • Sugimoto K,
  • Akiyama T,
  • Shimizu N,
  • Matsumura N,
  • Hashimoto M,
  • Minami T,
  • Nose K,
  • Nozawa M,
  • Yoshimura K,
  • Uemura H

Journal volume & issue
Vol. Volume 9
pp. 141 – 143

Abstract

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Koichi Sugimoto,1,2 Takahiro Akiyama,2 Nobutaka Shimizu,1 Naoki Matsumura,1,2 Mamoru Hashimoto,1 Takafumi Minami,1 Kazuhiro Nose,1 Masahiro Nozawa,1 Kazuhiro Yoshimura,1 Hirotsugu Uemura1 1Department of Urology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan; 2Department of Urology, Sakai-Onshinkai Hospital, Sakai, Osaka, Japan Abstract: Acute urinary retention is the most common urological emergency. To resolve this emergency, urethral catheterization is performed. If the procedure fails and permanent transurethral catheterization is required, the patient’s quality of life is significantly affected. Therefore, catheter-free treatment is the ideal goal of therapy for patients with acute urinary retention. Especially, for women, placement of a catheter poses a cosmetic problem. Therefore, the aim of this study was to treat female patients who had already received urapidil/distigmine bromide with acotiamide. Acotiamide was administered at a dose of 100 mg three times daily for 2 weeks, and the outcome of trial without catheter was evaluated. Only female patients were enrolled for this study. Treatment proved successful and all patients become catheter free. Keywords: female, acute urinary retention, acotiamide hydrochloride hydrate

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