Nature Communications (Jul 2022)
Comparison of chromatin accessibility landscapes during early development of prefrontal cortex between rhesus macaque and human
- Xuelong Yao,
- Zongyang Lu,
- Zhanying Feng,
- Lei Gao,
- Xin Zhou,
- Min Li,
- Suijuan Zhong,
- Qian Wu,
- Zhenbo Liu,
- Haofeng Zhang,
- Zeyuan Liu,
- Lizhi Yi,
- Tao Zhou,
- Xudong Zhao,
- Jun Zhang,
- Yong Wang,
- Xingxu Huang,
- Xiaoqun Wang,
- Jiang Liu
Affiliations
- Xuelong Yao
- CAS Key Laboratory of Genome Sciences and Information, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
- Zongyang Lu
- University of Chinese Academy of Sciences
- Zhanying Feng
- University of Chinese Academy of Sciences
- Lei Gao
- CAS Key Laboratory of Genome Sciences and Information, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
- Xin Zhou
- State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Brain-Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences
- Min Li
- University of Chinese Academy of Sciences
- Suijuan Zhong
- State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University
- Qian Wu
- State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University
- Zhenbo Liu
- CAS Key Laboratory of Genome Sciences and Information, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
- Haofeng Zhang
- Obstetrics and Gynecology Medical Center of Severe Cardiovascular of Beijing Anzhen Hospital, Capital Medical University
- Zeyuan Liu
- University of Chinese Academy of Sciences
- Lizhi Yi
- CAS Key Laboratory of Genome Sciences and Information, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
- Tao Zhou
- School of Life Science and Technology, Shanghai Tech University
- Xudong Zhao
- Kunming Primate Research Center, Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences
- Jun Zhang
- Obstetrics and Gynecology Medical Center of Severe Cardiovascular of Beijing Anzhen Hospital, Capital Medical University
- Yong Wang
- University of Chinese Academy of Sciences
- Xingxu Huang
- School of Life Science and Technology, Shanghai Tech University
- Xiaoqun Wang
- University of Chinese Academy of Sciences
- Jiang Liu
- CAS Key Laboratory of Genome Sciences and Information, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
- DOI
- https://doi.org/10.1038/s41467-022-31403-3
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
The evolution of epigenetic regulation of brain development in primates is not well understood. Here, the authors perform a comparative study of epigenetic dynamics of early prefrontal cortex development between human and rhesus macaque, finding divergent regulatory elements that may be related to cognitive capacity.
