Pharmaceutical therapy of Q-wave acute myocardial infarction: effects on adrenal morphology and function

Abstract

Adrenal morphology and function were studied in intensively treated patients with Q-wave acute myocardial infarction (AMI). Adequate analgetic and thrombolytic therapy, as well as beta-adrenoblocker treatment, prevented adrenal medulla depletion. Contralateral adrenal reaction was heterogeneous. The results obtained provide a better understanding of adaptive reactions and medication action mechanisms in intensively treated patients with Q-wave AMI.

Keywords

• acute myocardial infarction
• adrenal morphology and function
• intensive therapy
• thrombolytics
• betajblockers
• corticosteroids
• analgetics