Delta Journal of Ophthalmology (Jul 2024)

A case of accelerated recovery in acute retinal pigment epitheliitis with early methylprednisolone intervention

  • Anchal Tripathi,
  • Sonali Bhalla,
  • Lav Pathak,
  • Perwez Khan

DOI
https://doi.org/10.4103/djo.djo_11_24
Journal volume & issue
Vol. 25, no. 3
pp. 180 – 183

Abstract

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We present a compelling case of acute retinal pigment epitheliitis (ARPE), also known as Krill’s disease, in a 26-year-old female ophthalmology resident, emphasizing the significance of early intervention and its impact on rapid symptom resolution. Comprehensive ocular examination, fluorescein angiography, and spectral domain-optical coherence tomography were employed for the diagnosis. The patient received pulsed methylprednisolone therapy that was initiated promptly due to professional exigencies. Within 3 days of initiating the methylprednisolone therapy, most of the symptoms, including central scotoma and visual impairment, resolved remarkably. This accelerated recovery challenges the conventional notion of ARPE as a self-limiting condition. The case underscores the importance of individualized treatment strategies in professional contexts, where swift resolution is imperative. Advanced imaging techniques, particularly spectral domain-optical coherence tomography, play a pivotal role in both diagnosis and monitoring the disease progression. Further research is crucial to refine the treatment protocols and unravel the intricacies of ARPE pathophysiology.

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